Set 10 years after the events of ''Return of the Living Dead 3'', the film starts out with Charles Garrison (Peter Coyote) traveling to Chernobyl to collect the last 6 canisters of Trioxin 5. Two Russian sellers take him to an empty power station which contains the Trioxin. One of the Russians get Trioxin on his hands, turning him into a zombie. Upon hearing screams, Garrison runs to see the zombie eating the other Russian partner. Garrison promptly shoots the zombie in the head.