The film focuses on a small group of overzealous scientists who hope to use Count Dracula's desiccated - but still alive - body to discover the secret of immortality. Elizabeth Blaine, working at the New Orleans morgue, receives Dracula's "corpse" from her friend and co-worker Luke following the events of Dracula 2000. Elizabeth examines the body and pricks her finger on a fang in what is supposed to be a human mouth. This leads her to alert her boyfriend Lowell, who is suffering from an ultimately fatal degenerative sickness. Lowell claims a wealthy investor wants to fund their research into the mysterious corpse.