Chakram (Prabhas) is a foreign returnee who has a dream of building a hospital at Pulivendula. He is in love with his colleague and his cousin Lakshmi (Asin), who studied with him abroad. He leaves her halfway through after he realizes he was struck with cancer. Not wanting to tell her, he moves to Hyderabad and stays in a place called "Sahara Colony". There, he tries to solve problems of the people in the colony. Seeing all this, another girl who is also named Lakshmi (Charmy Kaur) falls in love with Chakram. The rest is a heart-rending saga of Chakram's love station.