Set in 1979 Syosset, Long Island, New York, ''Lymelife'' follows two families, the Bartletts and the Braggs, who crumble when tangled relationships, real-estate problems, and Lyme disease converge in the heart of suburbia. 15-year-old Scott Bartlett is a gentle boy, radically different from his blustery father Mickey and mother Brenda. An outbreak of Lyme disease, as well as the accompanying paranoia, hits their community hard.