Twelve strangers embark on the Trans-Asia Express, a four-day train journey from Tehran to Istanbul. Amongst them are Marjan, a girl with a bag full of money and embezzlement documents, Moosa, a man searching for his lost sister, Atousa a beautiful femme fatale, Dr.Taheri, the train"s physician, and a couple of tourists. When Marjan"s bag is stolen, everyone becomes a suspect.