It is the year 2267. After the earth has become uninhabitable due to an ecological collapse, the remaining people live on overcrowded space stations in Earth's orbit. The young doctor Laura Portmann (Anna Katharina Schwabroh) is one of them. She hopes for a better future alongside her sister on the distant planet Rhea, but to get there, she needs money. She signs up with Kuiper Enterprises for a job on the decrepit cargo ship Kassandra, heading for an eight-year flight to unmanned Station #42 and back.