Soundarya aka Sweety (Anushka Shetty) is an overweight, brave, independent woman. She is slightly conscious about her weight but does not let it affect her. She falls in love with Abhishek (Arya (actor)), who was once a prospective groom for her and now a friend. She later finds out that he is in love with Simran (Sonal Chauhan). Sweety is devastated and joins a weight loss clinic called Size Zero as she thinks that her weight is the issue. One of her friends, Jyothi (Pavani Gangireddy), who is in the clinic with her, develops kidney problems because of the weight loss drugs given in the clinic. Sweety begins a crusade against the clinic. She is joined by Abhi and Simran. Abhi slowly starts to fall for Sweety. The rest of the movie is how Sweety triumphs in her crusade and gets her Prince Charming back.