The film follows rookie detective Jo Dee Fostar (Billy Zane) on his first case. It involves a serial killer, wanted for over 120 murders. To find the killer, he must enlist the help of convicted murderer, Dr. Animal Cannibal Pizza (Deluise). However, during the investigation, his girlfriend, Jane Wine (Charlene Tilton), is asked by her boss to take a large sum of money to the bank. Instead of doing this, she leaves town with the money. While hiding, she decides to rest at the Cemetery Motel, which is later revealed to be a cemetery named Motel after its owner, Antonio Motel. Jo must then enlist the help of Det. Balsam (Balsam) and Dr. Pizza to not only find the murderer, but also his missing girlfriend. All of this takes the cast on many adventures at the Cemetery Motel. In the final confrontation, most characters are revealed to be somebody else in disguise.