''Blonde Trouble'' picks up from the previous installment of the Andy Hardy saga with Andy on a train to begin his college career at Wainwright College. While on the train, he meets Kay Wilson (Bonita Granville), and learns that Wainright College has just become a coeducational institution. The Dean of Wainwright College (and soon to be Andy's faculty advisor), Dr. Standish (Herbert Marshall) is also on the train. Dr. Standish's identity is not revealed to Andy until later.