''Jeena Sirf Merre Liye'' is about childhood friends Karan (Tusshar Kapoor) and Pinky (Puja) (Kareena Kapoor). Pinky and her father come to a hill station every year during Pinky's school break. Pinky looks forward to coming here for one reason: Karan. They get separated after Puja's father (Vijayendra Ghatge), a tycoon, goes back to the city. Karan gets adopted by a man also from the city. Puja's father sends her to his brother's house out of the country. Time passes and the two live with each other's memories. They try to find each other but are unable to.