''Oru Indian Pranayakadha'' is a love story which shows the relationship between a trickish person named Aymanam Sidharthan (Fahadh Faasil) and a disciplined Canadian citizen of Malayali origin named Irene Gardner (Amala Paul). In the beginning, the story shows the political life of Sidharthan. He is the local youth wing leader political outfit. Protege of the district president of the party, Uthup Vallikkadan (Innocent), Sidharthan hopes to make it big in politics . However, his dreams are shattered when the party High command decides to nominate the daughter of one of the party's senior leader's daughter named Vimala Ramanathan (Muthumani). This leads the young politician in despair. During this time the girl Irene Gardner visits Kerala to shoot a documentary. She is in search of an assistant to help her in shoot the film and approaches Uthup. Uthup requests Sidharthan to meet her and assist her. Sidharthan unwillingly went but when Irene promises Indian rupee 2000 per day for the assistant, so Siddharthan, who has financial issues, agrees to help her.