In 1875, near Durango, Mexico, a group of renegade Comanche attack a peaceful village and kidnap the daughter of a Spanish aristocrat. They escape the Mexican Army by crossing into US territory. Jim Read (Dana Andrews), a frontier scout, is sent to investigate and ease tensions between the Mexicans and the Comanche. But long standing hatred and the profitable business of scalp-hunting does not help in resolving the conflict. Read is sent to negotiate with the Comanche chief, Quanah Parker (Kent Smith). Whilst searching for Quanah, Read sees Art Downey (Stacy Harris (actor)), a local scalp-hunter, shoot and injure a Comanche. Read rescues him and takes him to Quanah. Read however is himself accused of the shooting by Black Cloud (Henry Brandon (actor)), the renegade leader, until the injured brave recovers enough to clear his name. Read reveals to Quanah that they are cousins and that his mother was the sister of Quanah’s mother. Quanah swears loyalty to his white friend. Read leaves to fetch government officials to a peace council, but discovers a cavalry detachment that has been massacred by Black Cloud and his renegades. The Government official, Commissioner Ward (Lowell Gilmore), has ordered the cavalry to subdue the Indians, by force if necessary. Black Cloud attacks a column of cavalry troopers and captures Ward. Quanah and a large force of loyal Comanche intervene and threaten to attack Black Cloud. Vengeful Black Cloud kills Ward. In the ensuing battle, Read kills Downey and Black Cloud and peace is restored.