Senator Walter Chalmers sets his sights on bringing down notorious mob boss Pete Ross, relying on the testimony of Johnny, Ross's volatile brother, who is under protective custody in San Francisco, supervised by police lieutenant Frank Bullitt. However, when two skilled assassins enter the picture, Bullitt embarks on a relentless pursuit, unraveling a complex web of obstacles and betrayals. This gripping thriller culminates in an iconic car chase, etching its place in cinematic history.