Dan Hardesty (William Powell) is an escaped murderer, sentenced to hang. In Hong Kong, he meets Joan Ames (Kay Francis), a terminally ill woman, in a bar. They share a drink, then Dan breaks his glass, followed by Joan. Police Sergeant Steve Burke (Warren Hymer) captures Dan when he leaves (though out of sight of Joan) and escorts his prisoner aboard an ocean liner crossing the Pacific to San Francisco. On board, Dan jumps into the water in a bid to escape, dragging a Handcuffs (and non-swimmer) Steve with him, but spots Joan among the passengers and changes his mind. Once the ship is underway, he persuades Steve to remove his handcuffs. Dan and Joan fall in love on the month-long cruise, neither knowing that the other is under the shadow of death.