Dr. Luther Brooks (Sidney Poitier), an intern who has just passed the state board examination to qualify for his license to practice, is the first African-American doctor at the urban county hospital at which he trained. Because he lacks self-confidence, Brooks requests to work as a junior resident at the hospital for another year. Johnny (Dick Paxton) and Ray Biddle (Richard Widmark), brothers who were both shot in the leg by a policeman as they attempted a robbery, are brought to the hospital's prison ward. As Luther tends to the disoriented Johnny, he is bombarded with racist slurs by Ray, who grew up in Beaver Canal, the white working class section of the city. Believing that Johnny has a brain tumor, Luther administers a spinal tap, but Johnny dies during the procedure. Wondering if Ray's antagonism may have caused him to be careless, Luther consults his mentor, chief medical resident Dr. Daniel Wharton (Stephen McNally), and Wharton concedes that a brain tumor was only one possibility. Feeling that he must prove the accuracy of his diagnosis, Luther requests an autopsy, but Wharton informs him that according to state law, they cannot proceed without the permission of the deceased's family. When Ray refuses, as he does not want his brother's body to be cut up, Wharton confers with the head of the hospital, Dr. Sam Moreland (Stanley Ridges), about requisitioning an autopsy.