In 1492 Andalusia, during the Granada War, Aguilar de Nerha is accepted into the Assassins Brotherhood. He is assigned to protect Prince Ahmed de Emirate of Granada from the Knights Templar. In 1986, adolescent Callum "Cal" Lynch finds his mother killed by his father, Joseph, a modern-day Assassin. Gunmen led by Alan Rikkin, CEO of the Templars' Abstergo Foundation, arrive to capture Joseph, who convinces his son to escape.